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1

Facilitated transport of uracil and 5-fluorouracil, and permeation of orotic acid into cultured mammalian cells

Robert M. Wohlhueter, R. Scott McIvor, Peter G. W. Plagemann

Journal:

Journal of Cellular Physiology

Year:

1980

Language:

english

File:

PDF, 909 KB

english, 1980

2

7. Gene delivery and biodistribution in the brain and spinal cord following intrathecal administration of adeno-associated virus serotype 5 vector

Lalitha Belur, Carolyn Fairbanks, Lucy Vulchanova, Kelly Podetz-Pedersen, Walter Low, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

3

Modifiable Risk Factors for Vascular Access Site Complications in the IMPACT II Trial of Angioplasty With Versus Without Eptifibatide

Jeffrey S. Mandak, James C. Blankenship, Laura H. Gardner, Scott D. Berkowitz, Frank V. Aguirre, Kristina N. Sigmon, Gerald C. Timmis, Ian C. Gilchrist, Michael McIvor, Jon Resar, Bonnie H. Weiner, Ba

Journal:

Journal of the American College of Cardiology

Year:

1998

Language:

english

File:

PDF, 75 KB

english, 1998

4

ZFN-mediated in vivo genome editing of hepatocytes results in phenotypic correction in murine MPS I and MPS II models

Wechsler, Thomas, DeKelver, Russell, Laoharawee, Kanut, Ou, Li, Tom, Susan, Radecke, Robert, Sproul, Scott, Koniar, Brenda L., Podetz-Perdersen, Kelly, Cooksley, Renee D., Meyer, Kathleen, McIvor, Sco

Journal:

Molecular Genetics and Metabolism

Year:

2018

Language:

english

File:

PDF, 70 KB

english, 2018

5

A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver

Kirk J. Wangensteen, Andrew Wilber, Vincent W. Keng, Zhiying He, Ilze Matise, Laura Wangensteen, Corey M. Carson, Yixin Chen, Clifford J. Steer, R. Scott McIvor, David A. Largaespada, Xin Wang, Stephe

Journal:

Year:

2008

Language:

english

File:

PDF, 983 KB

english, 2008

6

Uridine phosphorylase from Novikoff rat hepatoma cells: Purification, kinetic properties, and its role in uracil anabolism

R. Scott McIvor, Robert M. Wohlhueter, Peter P. G. Plagemann

Journal:

Journal of Cellular Physiology

Year:

1985

Language:

english

File:

PDF, 813 KB

english, 1985

7

Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses

Elena L. Aronovich, Jason B. Bell, Lalitha R. Belur, Roland Gunther, Brenda Koniar, David C. C. Erickson, Patricia A. Schachern, Ilze Matise, R. Scott McIvor, Chester B. Whitley, Perry B. Hackett

Journal:

The Journal of Gene Medicine

Year:

2007

Language:

english

File:

PDF, 1.41 MB

english, 2007

8

Sleeping Beauty-mediated correction of Fanconi anemia type C

Kendra A. Hyland, Erik R. Olson, Karl J. Clark, Elena L. Aronovich, Perry B. Hackett, Bruce R. Blazar, Jakub Tolar, R. Scott McIvor

Journal:

The Journal of Gene Medicine

Year:

2011

Language:

english

File:

PDF, 228 KB

english, 2011

9

An improved enzymatic radioassay for ribose 1-phosphate

R.Scott McIvor, Robert M. Wohlhueter, Peter G.W. Plagemann

Journal:

Analytical Biochemistry

Year:

1982

Language:

english

File:

PDF, 436 KB

english, 1982

10

Direct gene transfer to the CNS prevents emergence of neurologic disease in a murine model of mucopolysaccharidosis type I

Daniel A. Wolf, Andrew W. Lenander, Zhenhong Nan, Lalitha R. Belur, Chester B. Whitley, Pankaj Gupta, Walter C. Low, R. Scott McIvor

Journal:

Neurobiology of Disease

Year:

2011

Language:

english

File:

PDF, 2.03 MB

english, 2011

11

Gene therapy of genetic diseases and cancer

R. Scott McIvor

Journal:

Pediatric Transplantation

Year:

1999

Language:

english

File:

PDF, 74 KB

english, 1999

12

Conditional gene expression in the mouse using aSleeping Beautygene-trap transposon

Aron M Geurts, Andrew Wilber, Corey M Carlson, Paul D Lobitz, Karl J Clark, Perry B Hackett, R Scott McIvor, David A Largaespada

Journal:

BMC Biotechnology

Year:

2006

Language:

english

File:

PDF, 1.30 MB

english, 2006

13

Inhibition of angiogenesis and suppression of colorectal cancer metastatic to the liver using theSleeping BeautyTransposon System

Lalitha R Belur, Kelly M Podetz-Pedersen, Brent S Sorenson, Alice H Hsu, Josh B Parker, Cathy S Carlson, Daniel A Saltzman, S Ramakrishnan, R Scott McIvor

Journal:

Molecular Cancer

Year:

2011

Language:

english

File:

PDF, 1.53 MB

english, 2011

14

Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture

Vulchanova, Lucy, Schuster, Daniel J, Belur, Lalitha R, Riedl, Maureen S, Podetz-Pedersen, Kelly M, Kitto, Kelley F, Wilcox, George L, McIvor, R Scott, Fairbanks, Carolyn A

Journal:

Year:

2010

Language:

english

File:

PDF, 2.34 MB

english, 2010

15

Adeno-associated virus type 2 vectors: transduction and long-term expression in cerebellar Purkinje cells in vivo is mediated by the fibroblast growth factor receptor 1

Lalitha R. Belur, William F. Kaemmerer, R. Scott McIvor, Walter C. Low

Journal:

Archives of Virology

Year:

2008

Language:

english

File:

PDF, 239 KB

english, 2008

16

Methotrexate-Resistant Form of Dihydrofolate Reductase Protects Transgenic Murine Embryos from Teratogenic Effects of Methotrexate

Cari Sutton, R. Scott McIvor, Micki Vagt, Barbara Doggett, Raj P. Kapur

Journal:

Pediatric and Developmental Pathology

Year:

1998

Language:

english

File:

PDF, 998 KB

english, 1998

17

Counterselection and Co-Delivery of Transposon and Transposase Functions forSleeping Beauty-Mediated Transposition in Cultured Mammalian Cells

Andrea D. Converse, Lalitha R. Belur, Jennifer L. Gori, Geyi Liu, Felipe Amaya, Estuardo Aguilar-Cordova, Perry B. Hackett, R. Scott McIvor

Journal:

Bioscience Reports

Year:

2004

Language:

english

File:

PDF, 433 KB

english, 2004

18

Herpes simplex virus thymidine kinase enzymatic assay in transient transfection experiments using thymidine kinase-deficient cells

Jon J. Jonsson, R.Scott McIvor

Journal:

Analytical Biochemistry

Year:

1991

Language:

english

File:

PDF, 692 KB

english, 1991

19

A method for lifelong genetic manipulation of regenerating hepatocytes in mouse

Wangensteen, Kirk J, Wilber, Andrew, Keng, Vincent W, Chen, Yixin, Matise, Ilze, Wangensteen, Laura, Steer, Clifford J, McIvor, R Scott, Largaespada, David A, Wang, Xin

Journal:

Year:

2008

Language:

english

File:

PDF, 235 KB

english, 2008

20

Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection

Bell, Jason B, Podetz-Pedersen, Kelly M, Aronovich, Elena L, Belur, Lalitha R, McIvor, R Scott, Hackett, Perry B

Journal:

Nature Protocols

Year:

2007

Language:

english

File:

PDF, 761 KB

english, 2007

21

Lung-directed gene therapy in mice using the nonviral Sleeping Beauty transposon system

Belur, Lalitha R, Podetz-Pedersen, Kelly, Frandsen, Joel, McIvor, R Scott

Journal:

Nature Protocols

Year:

2007

Language:

english

File:

PDF, 243 KB

english, 2007

22

Sarcoma Derived from Cultured Mesenchymal Stem Cells

Jakub Tolar, Alma J. Nauta, Mark J. Osborn, Angela Panoskaltsis Mortari, Ron T. McElmurry, Scott Bell, Lily Xia, Ning Zhou, Megan Riddle, Tania M. Schroeder, Jennifer J. Westendorf, R. Scott McIvor, P

Journal:

Year:

2007

Language:

english

File:

PDF, 861 KB

english, 2007

23

Efficient and Stable Transgene Expression in Human Embryonic Stem Cells Using Transposon-Mediated Gene Transfer

Andrew Wilber, Jonathan L. Linehan, Xinghui Tian, Petter S. Woll, Julie K. Morris, Lalitha R. Belur, R. Scott McIvor, Dan S. Kaufman

Journal:

Year:

2007

Language:

english

File:

PDF, 2.02 MB

english, 2007

24

Deletion in a recombinant retroviral vector resulting from a cryptic splice donor signal in the moloney leukemia virus envelope gene

Journal:

Year:

1990

Language:

english

File:

PDF, 367 KB

english, 1990

25

Assay for expression of methotrexate-resistant dihydrofolate reductase activity in the presence of drug-sensitive enzyme

Kirstin Thompson, Dani Bich-Nga Vinh, R. Scott McIvor

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

1992

Language:

english

File:

PDF, 734 KB

english, 1992

26

Maintenance of differential methotrexate toxicity between cells expressing drug-resistant and wild-type dihydrofolate reductase activities in the presence of nucleosides through nucleoside transport inhibition

Christopher A Warlick, Colin L Sweeney, R.Scott McIvor

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 507 KB

english, 2000

27

Gene therapy for chronic myelogenous leukemia

Catherine M. Verfaillie, R.Scott McIvor, Robert C.H. Zhao

Journal:

Molecular Medicine Today

Year:

1999

Language:

english

File:

PDF, 210 KB

english, 1999

28

Dynamic Gene Expression After Systemic Delivery of Plasmid DNA as Determined by In Vivo Bioluminescence Imaging

Wilber, Andrew, Frandsen, Joel L., Wangensteen, Kirk J., Ekker, Stephen C., Wang, Xin, McIvor, R. Scott

Journal:

Human Gene Therapy

Year:

2005

Language:

english

File:

PDF, 305 KB

english, 2005

29

“Supercharged Cells” for Delivery of Recombinant Human Iduronate-2-Sulfatase

Dao Pan, Jon J. Jonsson, Stephen E. Braun, R.Scott McIvor, Chester B. Whitley

Journal:

Molecular Genetics and Metabolism

Year:

2000

Language:

english

File:

PDF, 166 KB

english, 2000

30

Saturation mutagenesis at dihydrofolate reductase codons 22 and 31 A variety of amino acid substitutions conferring methotrexate resistance

Jill A. Morris, R. Scott McIvor

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.50 MB

english, 1994

31

Awakening gene therapy with Sleeping Beauty transposons

Jeffrey J Essner, R Scott McIvor, Perry B Hackett

Journal:

Current Opinion in Pharmacology

Year:

2005

Language:

english

File:

PDF, 152 KB

english, 2005

32

11 Adeno-associated virus vector-mediated gene therapy in a murine model of mucopolysaccharidosis type I

Lalitha Belur, Zachary deMorest, Chester B. Whitley, Walter C. Low, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2007

Language:

english

File:

PDF, 58 KB

english, 2007

33

4. Sleeping Beauty transposon-mediated long-term α-l-iduronidase expression and correction of lysosomal pathology in NOD/SCID mice with MPS I

Elena Aronovich, Jason Bell, Lalitha Belur, Rolund Gunther, Koniar Brenda, Shaukat Kahn, Patricia Schachern, Robert Ehlenfeldt, Pankaj Gupta, Cathy Carlson, Chester Whitley, R. Scott McIvor, Perry Hac

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

34

69. Gene therapy of mucopolysaccharidosis type I: Intraventricular administration of adeno-associated virus vector transducing the human alpha-l-iduronidase gene in a murine model of the disease

R. Scott McIvor, Daniel A. Wolf, Zhenhong Nan, Mayra Quito, Kelly Podetz-Pedersen, Chester B. Whitley, Walter C. Low, Lalitha R. Belur

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

35

70. Gene therapy for lysosomal storage disorders

R. Scott McIvor, Walter C. Low, Perry B. Hackett, Chester B. Whitley

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

36

37. Comparison of gene expression in vivo from Sleeping Beauty transposons after hydrodynamic delivery or condensation by polyethylenimine and cationic lipids

Perry Hackett, Kelly Podetz-Pedersen, Jason Bell, Elena Aronovich, Betsy Kren, Chester Whitley, Wouter Driessen, Sean Sullivan, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 45 KB

english, 2008

37

107. Syngeneic bone marrow transplantation in a murine model of mucopolysaccharidosis type I

Daniel A. Wolf, Kelly M. Podetz-Pedersen, Jennifer L. Gori, Walter C. Low, Chester B. Whitley, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

38

64. Targeting neural stem cells in the mammalian brain with intraventricular injections of lenti, AAV5, or Sleeping Beauty vectors

Walter Low, Terry Burns, Catherine Verfaillie, Perry Hackett, Chet Whitley, Zhenghong Nan, Feng Xiao, Lalitha Belur, Zach Demorest, Dan Wolf, John Ohlfest, Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 43 KB

english, 2008

39

65. Gene therapy of MPS I mice using the Sleeping Beauty Transposon system

Perry Hackett, Elena Aronovich, Jason Bell, Shaukat Khan, Roland Gunther, Josh Parker, Cathy Carlson, Chester Whitley, R. Scott McIvor, Pankaj Gupta

Journal:

Molecular Genetics and Metabolism

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

40

86. Ex vivo lentiviral gene transfer targeting hematopoietic stem cells for therapy of mucopolysaccharidosis type II, Hunter syndrome

R. Scott McIvor, Daniel A. Wolf, Kelly Podetz-Petersen, Zhenhong Nan, Chester B. Whitley, Joseph Muenzer, Paul J. Orchard, Walter C. Low

Journal:

Molecular Genetics and Metabolism

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

41

153. Syngeneic Bone marrow transplantation in a murine model of mucopolysaccharidosis type I

Daniel Wolf, Zhenhong Nan, Kelly Podetz-Pedersen, Jennifer Gori, Brenda Koniar, Chester Whitley, Walter Low, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2009

Language:

english

File:

PDF, 41 KB

english, 2009

42

54. Hydrodynamic delivery of Sleeping Beauty transposons to canine liver via balloon catheters

Perry Hackett, Myra Urness, Jason Bell, Elena Aronovich, Eric Olson, David Hunter, Scott Mcivor

Journal:

Molecular Genetics and Metabolism

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

43

152. Long-term biochemical and neurobehavioral correction in a murine model of mucopolysaccharidosis type I following neonatal intracerebroventricular administration of a therapeutic adeno-associated virus vector

Daniel Wolf, Zhenhong Nan, Lalitha Belur, Debra Swanson, Andrew Lenander, Chester Whitley, Pankaj Gupta, Walter Low, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

44

Comparison of intraventricular vs. endovascular AAV5 mediated IDUA gene delivery to the brain in the MPS-I mouse model

Christopher Janson, Crusoe Nan, Lalitha Belur, Scott McIvor, Walter Low

Journal:

Molecular Genetics and Metabolism

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

45

Prolonged High-Level Expression of IDUA from Sleeping Beauty Transposons in Immunocompetent Mice

Elena Aronovich, Jason Bell, Kelly Podetz-Petersen, Brenda Koniar, R. Scott McIvor, Perry Hackett

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

46

Spatial Navigation and Working Memory Tests Demonstrate Neurological Deficits in a Murine Model of Mucopolysaccharidosis Type II (Hunter Syndrome)

Zhenhong Crusoe Nan, Kelly M. Podetz-Pedersen, Joseph Muenzer, Walter C. Low, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

47

Lysosomal enzyme can bypass the blood–brain barrier and reach the CNS following intranasal administration

Daniel A. Wolf, Leah R. Hanson, Elena L. Aronovich, Zhenhong Nan, Walter C. Low, William H. Frey II, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 424 KB

english, 2012

48

17β-Hydroxysteroid dehydrogenase type 7 (Hsd17b7) reverts cholesterol auxotrophy in NS0 cells

Gargi Seth, R. Scott McIvor, Wei-Shou Hu

Journal:

Journal of Biotechnology

Year:

2006

Language:

english

File:

PDF, 232 KB

english, 2006

49

Mammalian Expression of Cloned cDNA Sequences Encoding Human Purine Nucleoside Phosphorylase and Adenosine Deaminase

R. SCOTT McIVOR, DINKO VALERIO, STEVEN R. WILLIAMS, JUDY M. GODDARD, CHRISTIAN C. SIMONSEN, MARJA G. C. DUYVESTEYN, HANS VAN ORMONDT, ALEX J. VAN DER EB, DAVID W. MARTIN JR.

Journal:

Annals of the New York Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 321 KB

english, 1985

50

An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells

Filareto, Antonio, Parker, Sarah, Darabi, Radbod, Borges, Luciene, Iacovino, Michelina, Schaaf, Tory, Mayerhofer, Timothy, Chamberlain, Jeffrey S., Ervasti, James M., McIvor, R. Scott, Kyba, Michael,

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 1.98 MB

english, 2013